Oxymetholone is without a doubt the strongest and most visibly active steroid to date. Not only does it act very rapidly, it causes a virtual explosion of mass. Gains of up to 10 pounds in 2 weeks are not uncommon. This is largely due to a moderate to low androgenic effect combined with a high anabolic activity also mediated by non-AR mechanisms (mechanisms other than simply binding the androgen receptor). You can imagine that the gains made on oxymetholone aren’t the leanest. You would note a drastic smoothing out of the muscle due to estrogen-related fat (lipolysis) and water retention. This lipolysis has been shown to be rather drastic. One study1 on long-term hemodialysis patients showed beyond a doubt the role that oxymetholone can play in causing hyperlipedemia. The fat deposition rate, post-hepatic (after processing by the liver), increased drastically in the oxymetholone group while numbers remained stable in the control group._x000D__x000D_ It has been suggested that the estrogenic effects of oxymetholone may not be as much mediated by estrogen, as by oxymetholone itself activating the estrogen receptor. Because there is little to no aromatisation off oxymetholone, the possible progestational effect was examined first. Similar to that of nandrolone perhaps. But a study2 testing the progestational effects of oxymetholone and methandrostenolone against those of testosterone as well as nandrolone and its metabolites showed that the progestagenic activity of oxymetholone wasn’t even in the neighbourhood of that of testosterone, let alone nandrolone. Ruling out the possibility of progestagenic activity and aromatisation, that only left oxymetholone engaging in a structure with the estrogen receptor itself. Since it has an A-ring similar to that of estradiol (the prime estrogen) so this would be the most logical explanation. Since progesterone acts as an estrogen agonist, it would require circulating estrogen to negotiate such levels of water build-up as oxymetholone causes, so it seemed like a far-fetched idea to begin with._x000D__x000D_ _x000D__x000D_ Androlic / Anadrol tablets. Each anadrol tablet contains 50mg oxymetholone. Androlic / Anadrol, brand name Androlic, comes in packs of 20 tablets and is manufactured by The British Dispensary (L.P.) Co.Ltd._x000D__x000D_ _x000D__x000D_ The primary medical uses of anabolic-androgenic steroids are to treat delayed puberty, some types of impotence and wasting of the body caused by HIV infection or other diseases._x000D__x000D_ _x000D__x000D_ Anabolic steroids promote the growth of skeletal muscle and the development of male sexual characteristics but do also have some other effects._x000D__x000D_ Androlic / Anadrol 50 is the strongest and, at the same time, also the most effective oral steroid. Androlic / Anadrol has an extremely high androgenic effect, which goes hand in hand with an extremely intense anabolic component – oxymetholone. The highly androgenic effect of anadrol stimulates the regeneration of the body so that the often feared “over training” is unlikely to occur._x000D__x000D_ Anabolic steroids are synthetic derivatives of testosterone. Nitrogen balance is improved with anabolic agents but only when there is sufficient intake of calories and protein. Whether this positive nitrogen balance is of primary benefit in the utilization of protein-building dietary substances has not been established. Oxymetholone enhances the production and urinary excretion of erythropoietin in patients with anemias due to bone marrow failure and often stimulates erythropoiesis in anemias due to deficient red cell production._x000D__x000D_ Certain clinical effects and adverse reactions demonstrate the androgenic properties of this class of drugs. Complete dissociation of anabolic and androgenic effects has not been achieved. The actions of anabolic steroids are therefore similar to those of male sex hormones with the possibility of causing serious disturbances of growth and sexual development if given to young children. They suppress the gonadotropic functions of the pituitary and may exert a direct effect upon the testes.